Cat allergy is the most common animal allergy in the United States, and is a strong risk factor for asthma.   In fact,
cat allergy was found to account for almost a third of all asthma cases in a 2007 study performed by the National
Institute of Health.    

What causes cat allergy?
A common misconception is that cat allergic individuals are allergic to cat hair and that long haired cats are more
allergenic than short haired cats.    However,  this is no the case.    Cat allergy does not come from the hair itself,
but from proteins which stick on the hair.   The hair particles then become airborne and are subsequently inhaled
into the nose and lungs, resulting in allergy symptoms.

The major cat allergen is a tiny protein found in saliva and sweat called Fel d 1.    Another important cat allergen is
cat albumin (called Fel d 2) which is found in cat urine and skin dander.   As the cat grooms itself, it will spread the
allergens over its fur by licking itself.   All cats produce allergens, although some cats produce more than others.    
Overall, male cats produce more allergens than female cats, but the difference is not significant enough to make a
difference for most individuals allergic to cats.   

Cat allergens are transferred from place to place by floating in the air and by sticking on clothing and hair, making
them detectable in locations where cats are not normally found, such as shopping malls, movie theaters, hotels, and
doctor offices, and for this reason, it is nearly impossible to avoid cat allergen exposure.   In fact, several studies
showed that:
  • 56% of homes that never had cats contained levels of cat allergens high enough to sensitize people to cat
    allergy.
  • 16% of homes which never had cats contained levels of cat allergens high enough to cause asthma
    symptoms.
  • Within 3 weeks, new mattresses in stores had the same level of cat allergens as those in houses where cats
    used to live.
  • It may take up to 6 months after removal of a cat for the bulk of cat allergens to disappear from the home.
  • It can take up to 5 years for cat allergens in mattresses to decrease to levels found in homes without cats.

How to minimize cat allergens in the home
Removing the cat from the house is the best way to improve cat allergies.   Keeping the cat out of the bedroom is
not very effective since cat allergen is transferred from room to room by the owner’s clothing.   Remember that it
can take a good 6 months before the cat allergen levels are low enough that they will not longer be a problem.

If removing the cat from the house is not possible, some studies demonstrate that doing
all the following measures
together may help
  • Minimize carpeting.    Go for linoleum, tile, or hardwood floors.
  • Minimize upholstered furniture.  Go for leather furniture.
  • Vacuum floors, carpets, and furniture weekly.   Make sure the vacuum has a HEPA filter.
  • Wet mop floors weekly
  • Wipe walls and furniture weekly.   Dust cleaners such as the Swiffer® and Grab-It™ dust cloths work
    quite well.
  • Wash the cat at least weekly – this will help decrease the allergens on the skin and hair.  
  • Wash bedding at 130˚ F (60˚ C) weekly
  • Keep the cat out of all bedrooms
  • Close closets at all times when not in use

Diagnosis of Cat allergy
Cat allergy is diagnosed with a skin or blood test.

Treatment of cat allergy
Along with avoidance, medications such as antihistamines (Benadryl, Allegra, Claritin, Zyrtec,…) and steroid nose
sprays (Flonase, Nasonex, Rhinocort,…) can help minimize allergy symptoms.    
Allergy shots (immunotherapy)
has been demonstrated to be effective for the long term treatment of cat allergies.   


Sources:
Arbes S et al.  Asthma cases attributable to atopy: Results from the Third National Health and Nutrition
Examination Survey  
J Allergy Clin Immunol 207;120:1139-45.
Custovic A et al. Controlling indoor allergens
Ann Allergy Asthma Immunol 2002;88:432-442.
Björnsdottir US et al. The Effect of reducing levels of cat allergen (Fel d 1) on clinical symptoms in patients with
cat allergy.
Ann Allergy Asthma Immunol 2003:91:189-194.
Egmar AC et al. Deposition of cat, dog, and horse allergen over time in public environments-a model of
dispersion.  
Allergy 1998;53:957-961.
Wood RA et al. The effect of cat removal on allergen content in the household dust samples.
J Allergy Clin
Immunol
1989;83:730-734.
Allergen immunotherapy: A practice parameter second update  
J Allergy Clin Immunol 2007;120:s26-s85
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Cat Allergy

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